Since the advent of hybridoma technology, introduced by Kohler and Milstein in 1976, monoclonal antibodies have served as complementary elements in the areas of genetic research, immunology, and therapeutic applications. At the University of Chicago, this technology was pioneered by Dr. Frank Fitch in the Department of Pathology, who generated many monoclonal antibodies still used today in the field of Immunology. In 1995, the Frank W. Fitch Monoclonal Antibody Facility was created to promote this technology and make core services available to the University of Chicago community. The facility’s goal is to work closely with investigators to offer comprehensive hybridoma and protein production services, using state-of-the-art technology, suited to the specific basic science research or clinical needs of the investigator. Antibody and protein production services include: