|>> Large-Scale Protein Production using Hollow Fiber Bioreactors >> Protein Purification >> Protein Conjugation|
Mammalian cell cultures, for years, have been grown in 2-dimensional, non-porous, culture plates. These plates limit cell growth by needing to be split or passed and given fresh media every few days. After about 2 days, the cells have nearly consumed all the nutrients and are bathing in their waste. This feast and famine routine inhibits cells full potential as far a growth rates and antibody/protein secretion rates. The Hollow-Fiber Bioreactor technology addresses all these concerns.